Structures of β1-adrenergic receptor in complex with Gs and ligands of different efficacies
oleh: Minfei Su, Navid Paknejad, Lan Zhu, Jinan Wang, Hung Nguyen Do, Yinglong Miao, Wei Liu, Richard K. Hite, Xin-Yun Huang
| Format: | Article |
|---|---|
| Diterbitkan: | Nature Portfolio 2022-07-01 |
Deskripsi
Su et al. report cryo-EM structures of β1-adrenergic receptor, Gs and ligands of different efficacies. These complexes have similar overall architecture, but with local conformational differences and different stabilities.