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Cytomegalovirus (CMV) is recognized pathogen known for most common intrauterine infection in humans and vertical transmissions. We present a case of congenital CMV infection with bilateral cataract which is complicated by cholelithiasis which was later diagnosed on ultrasound examination of abdomen. This case is of particular interest because cholelithiasis has never been reported with CMV infection in literature. Patient had no history of any immune deficiency, any hemolytic or bowel disease.