Preparation of 2-heteroatom substituted 4-oxo-4-arylbutanoates via thio- and aza-Michael addition
oleh: Liu Huili, Lv Xin, Zhou Liejin, Yin Ruifeng, Wang Xiaoxia
| Format: | Article |
|---|---|
| Diterbitkan: | Serbian Chemical Society 2012-01-01 |
Deskripsi
Efficient regioselective conjugate additions of thiophenols and benzotriazole to 4-aryl-4-oxobut-2-enoates have been achieved under mild conditions. Thus a variety of 2-arylthio-4-oxo-4-arylbutanoates and 2- benzotriazolyl-4-oxo-4-arylbutanoates were conveniently synthesized in good to excellent yields.