Synthesis of 14-Substituted-14H-Dibenzo[<i>a,j</i>]Xanthene Derivatives in Presence of Effective Synergetic Catalytic System Bleaching Earth Clay and PEG-600
oleh: Sandeep T. Atkore, Giribala M. Bondle, Pranita V. Raithak, Vinod T. Kamble, Ravi Varala, Mufsir Kuniyil, Mohammad Rafe Hatshan, Baji Shaik, Syed Farooq Adil, Mohammed Althaf Hussain
| Format: | Article |
|---|---|
| Diterbitkan: | MDPI AG 2021-10-01 |
Deskripsi
The synthesis of 14-aryl 14H-dibenzo[<i>a,j</i>]xanthenes is achieved by a simple condensation reaction between β-naphthol with aryl or alkyl aldehydes in an effective synergetic catalytic system created by combining basic bleaching earth clay and PEG-600. The advantages of the present method include catalyst recyclability, superior product yield, a shorter reaction time and the avoidance of hazardous reagents. Synthesized xanthene derivatives were also screened for their antibacterial activity against <i>Staphylococcus aureus</i> (MTCC 96) and <i>Pseudomonas aeruginosa</i> (Wild).