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Scientific representation on paroxysmal brain and stages of the brain epileptisation on regional population of epileptic patients (more than 6000 cases) and clinical material consisting of 341 patients whom had been observed not less than 6 years has been established. Statements of the compensation and decompensation of the diseases process on the stages of progressing and seizure control are argumented. Criteria for restoring epilepsy defending mechanisms over a long period of time disease remission are stated. Described proposals and recommendations are tested on large group of patients.