5-{[(3R,5aS,6R,8aS,9R,10S,12R,12aR)-3,6,9-Trimethylperhydro-3,12-epoxy-1,2-dioxepino[4,3-i]isochromen-10-yl]oxymethyl}benzene-1,3-diol
oleh: Mahmoud A. El Sohly, Mitchell A. Avery, Ahmed Galal, Paulo Carvalho, Waseem Gul
| Format: | Article |
|---|---|
| Diterbitkan: | International Union of Crystallography 2009-02-01 |
Deskripsi
The title compound, C22H30O7, is a fused five-ring system that is of interest for its anticancer and antimalarial activity. The six-membered C6 and C5O rings display chair conformations. The six-membered C3O3 ring containing the ether and peroxy functionalities has a distorted boat conformation, with a C—O—O—C torsion angle of 42.6 (1)° for the peroxy group. The seven-membered C6O ring has a distorted boat-type conformation, while the seven-membered C5O2 ring has a very distorted chair-type conformation. The structure contains intermolecular O—H...O and O—H...(O,O) bonds that link the molecules into sheets parallel to the (100) planes.