Genome-wide analysis of chromosomal import patterns after natural transformation of Helicobacter pylori

oleh: Sebastian Bubendorfer, Juliane Krebes, Ines Yang, Elias Hage, Thomas F. Schulz, Christelle Bahlawane, Xavier Didelot, Sebastian Suerbaum

Format: Article
Diterbitkan: Nature Portfolio 2016-06-01

Deskripsi

Uptake and integration of exogenous DNA into the bacterial genome play an important role in the evolution of the pathogen Helicobacter pylori. Here, the authors describe a bimodal pattern of chromosomal integration and show how restriction-modification systems limit the import of heterologous DNA.