Thirty loci identified for heart rate response to exercise and recovery implicate autonomic nervous system

oleh: Julia Ramírez, Stefan van Duijvenboden, Ioanna Ntalla, Borbala Mifsud, Helen R Warren, Evan Tzanis, Michele Orini, Andrew Tinker, Pier D. Lambiase, Patricia B. Munroe

Format: Article
Diterbitkan: Nature Portfolio 2018-05-01

Deskripsi

Genome-wide association studies have identified multiple loci for resting heart rate (HR) but the genetic factors associated with HR increase during and HR recovery after exercise are less well studied. Here, the authors examine both traits in a two-stage GWAS design in up to 67,257 individuals from UK Biobank.