Discovery of New Eunicellin-Based Diterpenoids from a Formosan Soft Coral Cladiella sp.

oleh: Ping-Jyun Sung, Yang-Chang Wu, Nai-Cheng Lin, Lee-Shing Fang, Yu-Hsin Chen, Yin-Di Su, Yu-Chia Chang, Tsung-Hung Chen, Mei-Chin Lu

Format: Article
Diterbitkan: MDPI AG 2013-11-01

Deskripsi

A new eunicellin diterpenoid, cladieunicellin I (1), and a new natural eunicellin, litophynin I diacetate (2), were isolated from a Formosan soft coral identified as Cladiella sp. The structures of eunicellins 1 and 2 were elucidated by spectroscopic methods and by comparison of the spectral data with those of related analogues. Eunicellin 1 exhibited significant cytotoxicity toward the DLD-1 human colorectal adenocarcinoma cells.