Gold nanoparticles enhance antibody effect through direct cancer cell cytotoxicity by differential regulation of phagocytosis

oleh: Linyang Fan, Weizhi Wang, Zihua Wang, Minzhi Zhao

Format: Article
Diterbitkan: Nature Portfolio 2021-11-01

Deskripsi

Antibody therapies have huge potential in treating cancer but currently suffer from problems with delivery. Here the authors report on a study into then conjugation of Ramucirumab to gold nanoparticles to improve delivery and add theranostic capabilities, demonstrating preferential toxicity in gastric cancer cells.