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Mild traumatic brain injury (TBI) is defined as a Glasgow Coma Scale score of 13-15, and includes concussion, a broad constellation of clinical findings. The clinical findings can include headaches, changes in cognitive function, emotional lability, and cardiovascular, oculomotor, and vestibular dysfunction. While hyperosmolar therapy is a mainstay in medical therapy for moderate to severe TBI, limited evidence exists for its use in mild TBI.