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Wheat bran is the main by-product during the milling process of wheat flour,which is rich in bioactive substances.It could be used as the substrate for microbial growth in the process of solid-state fermentation and in various industrial production fields.The current research and application of solidstate fermented wheat bran in metabolites production,microbial inoculums preparation,whole-grain food processing,and feed substitution were reviewed in this study,and their prospects were also put forward,in order to provide a theoretical reference for the further and systematic research of wheat bran solid-state fermentation.