Stress-induced formation of cell wall-deficient cells in filamentous actinomycetes

oleh: Karina Ramijan, Eveline Ultee, Joost Willemse, Zheren Zhang, Joeri A. J. Wondergem, Anne van der Meij, Doris Heinrich, Ariane Briegel, Gilles P. van Wezel, Dennis Claessen

Format: Article
Diterbitkan: Nature Portfolio 2018-12-01

Deskripsi

Bacteria can be forced to grow without cell wall if cell wall synthesis is inhibited. Here Ramijan et al. show that, in filamentous actinomycetes, hyperosmotic stress induces formation of wall-deficient cells that can switch to normal mycelial growth, or mutate and proliferate indefinitely as wall-less forms.