Genome-wide association and HLA region fine-mapping studies identify susceptibility loci for multiple common infections

oleh: Chao Tian, Bethann S. Hromatka, Amy K. Kiefer, Nicholas Eriksson, Suzanne M. Noble, Joyce Y. Tung, David A. Hinds

Format: Article
Diterbitkan: Nature Portfolio 2017-09-01

Deskripsi

Susceptibility to infectious diseases is, among others, influenced by the genetic landscape of the host. Here, Tian and colleagues perform genome-wide association studies for 23 common infections and find 59 risk loci for 17 of these, both within the HLA region and non-HLA loci.