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Kawasaki disease, first described by Tomisaku Kawasaki in 1967, is an acute systemic vasculitis of infancy and childhood. It is now the leading cause of acquired heart disease in developed countries. The most common age group affected is between 6 months to 5 years and the peak incidence is in children aged 9 to 11 months. The disease has male preponderance with the male female ratio of 1.5:1. Though the exact etiology is not known the disease is known to be associated with unusual degree of immune activation and immunoregulatory abnormality.