Monitoring the binding and insertion of a single transmembrane protein by an insertase

oleh: Pawel R. Laskowski, Kristyna Pluhackova, Maximilian Haase, Brian M. Lang, Gisela Nagler, Andreas Kuhn, Daniel J. Müller

Format: Article
Diterbitkan: Nature Portfolio 2021-12-01

Deskripsi

The insertion and folding nascent or fully synthesized polypeptides into membranes is assisted by insertases. Here, the authors use a range of biophysical approaches to provide molecular details of how the transmembrane insertase YidC facilitates the insertion a protein into a phospholipid membrane.