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Duodenal carcinoma remains a very rare pathology, the most efficient therapeutic strategy remaining intensively debatable. However, it seems that the most appropriate therapeutic approach for each case can be established depending on the dimensions and stage of the tumor and according to the tumoral localization. Although initially it has been proposed that in all cases in which resection is feasible a duodenopancreatectomy should be performed, nowadays the therapeutic strategy has been submitted to permanent changes, more conservative approaches such as endoscopic full thickness resection or pancreas preserving duodenal resection being proposed with encouraging results. This is a literature review of the largest studies which investigated the feasibility of duodenal resections for duodenal malignant tumors.