Eliciting the impacts of cellular noise on metabolic trade-offs by quantitative mass imaging

oleh: A. E. Vasdekis, H. Alanazi, A. M. Silverman, C. J. Williams, A. J. Canul, J. B. Cliff, A. C. Dohnalkova, G. Stephanopoulos

Format: Article
Diterbitkan: Nature Portfolio 2019-02-01

Deskripsi

How cellular noise impacts metabolic trade-offs remains unknown. Here, the authors use a quantitative single-cell mass imaging strategy to reveal that cellular noise impacts cellular biomass and triacylglycerol accumulation, as well as protein and fatty-acid recycling under starvation, differently.