Targeted volumetric single-molecule localization microscopy of defined presynaptic structures in brain sections
oleh: Martin Pauli, Mila M. Paul, Sven Proppert, Achmed Mrestani, Marzieh Sharifi, Felix Repp, Lydia Kürzinger, Philip Kollmannsberger, Markus Sauer, Manfred Heckmann, Anna-Leena Sirén
| Format: | Article |
|---|---|
| Diterbitkan: | Nature Portfolio 2021-03-01 |
Deskripsi
Pauli et al. develop targeted volumetric dSTORM in order to image large hippocampal mossy fiber boutons (MFBs) in brain slices. They can identify synaptic targets of individual MFBs and measured size and density of Bassoon clusters within individual untruncated MFBs at nanoscopic resolution.