Nonattenuated Polymyxin B Used for the Treatment of Extreme-Drug Resistant Acinetobacter baumannii-Related Infections in Patients with Preexisting End Stage Renal Failure
oleh: Yvonne Peijun Zhou, Nathalie Grace Sy Chua, Maciej Piotr Chlebicki, Winnie Hui Ling Lee, Andrea Lay Hoon Kwa
| Format: | Article |
|---|---|
| Diterbitkan: | Wiley 2014-01-01 |
Deskripsi
Recent pharmacokinetic studies have suggested that nonrenal clearance predominates the elimination of polymyxin B. We present 2 patients with preexisting end stage renal failure, who were given nonattenuated doses of polymyxin B for the treatment of extreme-drug resistant organism. No evidence of adverse events occurred and microbiological clearance was documented.