Case report: Durable response after pembrolizumab in combination with radiation - induced abscopal effect in platinum - refractory metastatic endometrial clear cell carcinoma
oleh: Chien-Hsiang Kao, Chien-Ting Liu, Hao Lin, Yung-Cheng Huang, Jui Lan, Yu-Che Ou, Yu-Che Ou, Hung-Chun Fu, Chen-Hsuan Wu, Chen-Hsuan Wu
| Format: | Article |
|---|---|
| Diterbitkan: | Frontiers Media S.A. 2022-12-01 |
Deskripsi
Advanced endometrial clear cell carcinoma (CCC) tends to have poor prognosis owing to aggressive clinical behavior and poor response to conventional chemotherapy. Herein, we report a case of platinum-refractory recurrent ECCC successfully treated with the combination of pembrolizumab, localized radiotherapy and a few cycles of chemotherapy with an extremely durable response even after cessation of immunotherapy for 3 years at the time of publication.