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A minimal model for structure, dynamics, and tension of monolayered cell colonies
oleh: Debarati Sarkar, Gerhard Gompper, Jens Elgeti
Format: | Article |
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Diterbitkan: | Nature Portfolio 2021-02-01 |
Deskripsi
Cells are in constant movement inside tissues, but often remain cohesive nevertheless, i.e., single cells do not escape from the colony edges. Using an active Brownian-particle model with attraction, in this paper the authors develop an interaction potential that reproduces experimental observations describing the motion of epithelial sheets under different conditions.