A minimal model for structure, dynamics, and tension of monolayered cell colonies

oleh: Debarati Sarkar, Gerhard Gompper, Jens Elgeti

Format: Article
Diterbitkan: Nature Portfolio 2021-02-01

Deskripsi

Cells are in constant movement inside tissues, but often remain cohesive nevertheless, i.e., single cells do not escape from the colony edges. Using an active Brownian-particle model with attraction, in this paper the authors develop an interaction potential that reproduces experimental observations describing the motion of epithelial sheets under different conditions.