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Correlation of SARS-CoV-2 Subgenomic RNA with Antigen Detection in Nasal Midturbinate Swab Specimens
oleh: Katherine Immergluck, Mark D. Gonzalez, Jennifer K. Frediani, Joshua M. Levy, Janet Figueroa, Anna Wood, Beverly B. Rogers, Jared O’Neal, Roger Elias-Marcellin, Allie Suessmith, Julie Sullivan, Raymond F. Schinazi, Ahmed Babiker, Anne Piantadosi, Miriam B. Vos, Greg S. Martin, Wilbur A. Lam, Jesse J. Waggoner
Format: | Article |
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Diterbitkan: | Centers for Disease Control and Prevention 2021-11-01 |
Deskripsi
Among symptomatic outpatients, subgenomic RNA of severe acute respiratory syndrome coronavirus 2 in nasal midturbinate swab specimens was concordant with antigen detection but remained detectable in 13 (82.1%) of 16 nasopharyngeal swab specimens from antigen-negative persons. Subgenomic RNA in midturbinate swab specimens might be useful for routine diagnostics to identify active virus replication.