Cerebrospinal Fluid Immunoglobulins as Potential Biomarkers of Chikungunya Encephalitis
oleh: Marzia Puccioni-Sohler, Luiz Claudio Farias, Mauro Jorge Cabral-Castro, Mariano G. Zalis, Rosangela S. Kalil, Maria Cecília F. Salgado
| Format: | Article |
|---|---|
| Diterbitkan: | Centers for Disease Control and Prevention 2018-05-01 |
Deskripsi
Chikungunya virus causes fever and severe polyarthritis or arthralgia and is associated with neurologic manifestations that are sometimes challenging to diagnose. We demonstrate intrathecal synthesis of chikungunya antibodies in a patient with a history of acute infection complicated by encephalitis. The specificity of the intracerebral immune response supports early chikungunya-associated encephalitis diagnosis.