Improving the Precision of Base Editing by Bubble Hairpin Single Guide RNA
oleh: Zhiwei Hu, Yannan Wang, Qian Liu, Yan Qiu, Zhiyu Zhong, Kangdi Li, Wenhua Li, Zixin Deng, Yuhui Sun
| Format: | Article |
|---|---|
| Diterbitkan: | American Society for Microbiology 2021-04-01 |
Deskripsi
Base editors are double-strand-break (DSB)-free genome editing tools and have been widely used in diverse living systems. However, it is reported that these tools can cause substantial off-target editing.