Identification of a Zeb1 expressing basal stem cell subpopulation in the prostate
oleh: Xue Wang, Haibo Xu, Chaping Cheng, Zhongzhong Ji, Huifang Zhao, Yaru Sheng, Xiaoxia Li, Jinming Wang, Yu Shu, Yuman He, Liancheng Fan, Baijun Dong, Wei Xue, Chee Wai Chua, Dongdong Wu, Wei-Qiang Gao, Helen He Zhu
| Format: | Article |
|---|---|
| Diterbitkan: | Nature Portfolio 2020-02-01 |
Deskripsi
Heterogeneous populations of basal cells in the prostate epithelium contain stem cells. Here the authors show that Zeb1 marks a pool of prostate epithelial stem cells that self-renew, generate prostate glandular structures with all 3 epithelial cell types and are required for prostate basal cell development.