Phosphosite Scanning reveals a complex phosphorylation code underlying CDK-dependent activation of Hcm1
oleh: Michelle M. Conti, Rui Li, Michelle A. Narváez Ramos, Lihua Julie Zhu, Thomas G. Fazzio, Jennifer A. Benanti
| Format: | Article |
|---|---|
| Diterbitkan: | Nature Portfolio 2023-01-01 |
Deskripsi
Many kinases phosphorylate proteins on multiple sites, however in most cases it is not known which sites are functionally important. Here, the authors describe a high-throughput approach to quantitatively evaluate the contribution of each phosphosite within a multisite phosphorylated domain.