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We show renormalization in Quantum Brain Dynamics (QBD) in <inline-formula><math xmlns="http://www.w3.org/1998/Math/MathML" display="inline"><semantics><mrow><mn>3</mn><mo>+</mo><mn>1</mn></mrow></semantics></math></inline-formula> dimensions, namely Quantum Electrodynamics with water rotational dipole fields. First, we introduce the Lagrangian density for QBD involving terms of water rotational dipole fields, photon fields and their interactions. Next, we show Feynman diagrams with 1-loop self-energy and vertex function in dipole coupling expansion in QBD. The counter-terms are derived from the coupling expansion of the water dipole moment. Our approach will be applied to numerical simulations of Kadanoff–Baym equations for water dipoles and photons to describe the breakdown of the rotational symmetry of dipoles, namely memory formation processes. It will also be extended to the renormalization group method for QBD with running parameters in multi-scales.