Regulatory mechanisms of incomplete huntingtin mRNA splicing
oleh: Andreas Neueder, Anaelle A. Dumas, Agnesska C. Benjamin, Gillian P. Bates
| Format: | Article |
|---|---|
| Diterbitkan: | Nature Portfolio 2018-09-01 |
Deskripsi
Incomplete splicing of HTT results in the production of the highly pathogenic exon 1 HTT protein. Here the authors identify the necessary intronic regions and the underlying mechanisms that contribute to this process.