Drug Resistance Spread in 6 Metropolitan Regions, Germany, 2001–2018
oleh: Melanie Stecher, Antoine Chaillon, Christoph Stephan, Elena Knops, Niko Kohmer, Clara Lehmann, Josef Eberle, Johannes Bogner, Christoph D. Spinner, Anna Maria Eis-Hübinger, Jan-Christian Wasmuth, Guido Schäfer, Georg Behrens, Sanjay R. Mehta, Jörg Janne Vehreschild, Martin Hoenigl
| Format: | Article |
|---|---|
| Diterbitkan: | Centers for Disease Control and Prevention 2020-10-01 |
Deskripsi
We analyzed 1,397 HIV-1 pol sequences of antiretroviral therapy–naive patients in a total of 7 university hospitals in Bonn, Cologne, Frankfurt, Hamburg, Hannover, and Munich, Germany. Phylogenetic and network analysis elucidated numerous cases of shared drug resistance mutations among genetically linked patients; K103N was the most frequently shared mutation.