miR-122 removal in the liver activates imprinted microRNAs and enables more effective microRNA-mediated gene repression

oleh: Paul N. Valdmanis, Hak Kyun Kim, Kirk Chu, Feijie Zhang, Jianpeng Xu, Elizabeth M. Munding, Jia Shen, Mark A. Kay

Format: Article
Diterbitkan: Nature Portfolio 2018-12-01

Deskripsi

miR-122 is a highly expressed microRNA in the liver. Here the authors analyse the mouse liver microRNA landscape following depletion of miR-122 and the impact that this has on its target mRNAs.