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miR-122 removal in the liver activates imprinted microRNAs and enables more effective microRNA-mediated gene repression
oleh: Paul N. Valdmanis, Hak Kyun Kim, Kirk Chu, Feijie Zhang, Jianpeng Xu, Elizabeth M. Munding, Jia Shen, Mark A. Kay
Format: | Article |
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Diterbitkan: | Nature Portfolio 2018-12-01 |
Deskripsi
miR-122 is a highly expressed microRNA in the liver. Here the authors analyse the mouse liver microRNA landscape following depletion of miR-122 and the impact that this has on its target mRNAs.