Regulatory basis for reproductive flexibility in a meningitis-causing fungal pathogen

oleh: Pengjie Hu, Hao Ding, Huimin Liu, Yulin Yang, Lei Chen, Guang-Jun He, Weixin Ke, Ping Zhu, Xiuyun Tian, Yan Peng, Zhenghao Shen, Xiaoxia Yao, Changyu Tao, Ence Yang, Guojian Liao, Xiao Liu, Linqi Wang

Format: Article
Diterbitkan: Nature Portfolio 2022-12-01

Deskripsi

Pathogenic fungi of the genus Cryptococcus can undergo bisexual and unisexual reproduction. Here, the authors construct a gene-deletion library for over 100 transcription factor genes in Cryptococcus deneoformans and provide insights into regulatory cascades that are specific for each reproductive mode.