Dinuclear Zinc (II) Complexes of Macrocyclic Polyamine Ligands Containing an Imidazolium Bridge: Synthesis, Characterization, and Their Interaction with Plasmid DNA

oleh: Xiao-Qi Yu, Jiang Wu, Hong-Hui Lin, Ning Jiang, Kun Li, Qiang-Lin Li, Li-Hong Zhou, Ji Zhang, Qing-Dong Huang, Jun Huang

Format: Article
Diterbitkan: MDPI AG 2007-07-01

Deskripsi

Two novel macrocyclic polyamine ligands and their dinuclear zinc (II)complexes were synthesized and characterized. Their interaction with plasmid DNA wasstudied by gel electrophoresis and fluorescence quenching experiment. The result showedthat these complexes could bind DNA efficiently under physiological conditions.