Network-based machine learning in colorectal and bladder organoid models predicts anti-cancer drug efficacy in patients

oleh: JungHo Kong, Heetak Lee, Donghyo Kim, Seong Kyu Han, Doyeon Ha, Kunyoo Shin, Sanguk Kim

Format: Article
Diterbitkan: Nature Portfolio 2020-10-01

Deskripsi

Cancer patient classification using predictive biomarkers for anti-cancer drug responses is essential for improving therapeutic outcomes. Here, the authors present a machine-learning framework to identify robust drug biomarkers by taking advantage of network-based analyses using pharmacogenomic data.