Plasmodium falciparum pfhrp2 and pfhrp3 Gene Deletions in Malaria-Hyperendemic Region, South Sudan
oleh: Irene Molina-de la Fuente, María José Sagrado Benito, Laurence Flevaud, Janet Ousley, Harriet Akello Pasquale, Ahmed Julla, Abdirashid M. Abdi, Buai Tut Chol, Bakri Abubakr, Agustín Benito, Cristian Casademont, Carolina Nanclares, Pedro Berzosa
| Format: | Article |
|---|---|
| Diterbitkan: | Centers for Disease Control and Prevention 2023-01-01 |
Deskripsi
Pfhrp2 and pfhrp3 gene deletions threaten the use of Plasmodium falciparum malaria rapid diagnostic tests globally. In South Sudan, deletion frequencies were 15.6% for pfhrp2, 20.0% for pfhrp3, and 7.5% for double deletions. Deletions were approximately twice as prevalent in monoclonal infections than in polyclonal infections.