Whole Genome Sequencing of an Unusual Serotype of Shiga Toxin–producing Escherichia coli

oleh: Tim Dallman, Lisa Cross, Chloe Bishop, Neil Perry, Bente Olesen, Kathie A. Grant, Claire Jenkins

Format: Article
Diterbitkan: Centers for Disease Control and Prevention 2013-08-01

Deskripsi

Shiga toxin–producing Escherichia coli serotype O117:K1:H7 is a cause of persistent diarrhea in travelers to tropical locations. Whole genome sequencing identified genetic mechanisms involved in the pathoadaptive phenotype. Sequencing also identified toxin and putative adherence genes flanked by sequences indicating horizontal gene transfer from Shigella dysenteriae and Salmonella spp., respectively.