Molecular mechanism of the MORC4 ATPase activation
oleh: Adam H. Tencer, Khan L. Cox, Gregory M. Wright, Yi Zhang, Christopher J. Petell, Brianna J. Klein, Brian D. Strahl, Joshua C. Black, Michael G. Poirier, Tatiana G. Kutateladze
| Format: | Article |
|---|---|
| Diterbitkan: | Nature Portfolio 2020-10-01 |
Deskripsi
Human Microrchidia 4 (MORC4) ATPase has been implicated in acute and chronic pancreatitis, inflammatory disorders and cancer. Here the authors describe the structure–function relationship of MORC4 and define the molecular mechanism for MORC4 activation.