A MUB E2 structure reveals E1 selectivity between cognate ubiquitin E2s in eukaryotes
oleh: Xiaolong Lu, Konstantin R. Malley, Caitlin C. Brenner, Olga Koroleva, Sergey Korolev, Brian P. Downes
| Format: | Article |
|---|---|
| Diterbitkan: | Nature Portfolio 2016-08-01 |
Deskripsi
Regulators of the important ubiquitylation cascade are not well studied. Here, the authors report the crystal structure of a prenylated membrane-anchored ubiquitin-fold protein from Arabidopsisbound to an E2 protein and conclude that it is an example of selective activation between E2 enzymes.