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Nuclear export of the pre-60S ribosomal subunit through single nuclear pores observed in real time
oleh: Jan Andreas Ruland, Annika Marie Krüger, Kerstin Dörner, Rohan Bhatia, Sabine Wirths, Daniel Poetes, Ulrike Kutay, Jan Peter Siebrasse, Ulrich Kubitscheck
Format: | Article |
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Diterbitkan: | Nature Portfolio 2021-10-01 |
Deskripsi
Ribosomal biogenesis is known to require nuclear to cytoplasmic export, but the precise kinetics remain unclear. Here, the authors use super-resolution confocal microscopy and single molecule tracking to visualize export of single pre-60S particles through nuclear pore complexes.