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An Improved Scalable Synthesis of α- and β-Amyrin
oleh: Immo Serbian, René Csuk
Format: | Article |
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Diterbitkan: | MDPI AG 2018-06-01 |
Deskripsi
The synthesis of α- and β-amyrin was accomplished starting from easily accessible starting materials, oleanolic, and ursolic acid. The procedures allow the preparation of β-amyrin in an exceptionally short scalable manner via selective iodation and reduction. For α-amyrin, a different synthetic approach had to be chosen providing access to α-amyrin in medium-to-large scale.