Cross-Jurisdictional Transmission of Mycobacterium tuberculosis in Maryland and Washington, D.C., 1996–2000, Linked to the Homeless

oleh: Monica Lathan, Leonard Ntaate Mukasa, Nancy Hooper, Jonathan Golub, Nancy Baruch, Donna Mulcahy, William Benjamin, Wendy A. Cronin

Format: Article
Diterbitkan: Centers for Disease Control and Prevention 2002-11-01

Deskripsi

From 1996 to 2000, 23 Maryland and Washington, D.C., tuberculosis cases were identified in one six-band DNA cluster. Cases were clustered on the basis of their Mycobacterium tuberculosis isolates. Medical record reviews and interviews were conducted to identify epidemiologic linkages. Eighteen (78%) of the 23 case-patients with identical restriction fragment length polymorphism patterns were linked to another member; half the patients were associated with a Washington, D.C., homeless shelter. Molecular epidemiology defined the extent of this large, cross-jurisdictional outbreak.