A chiral selectivity relaxed paralog of DTD for proofreading tRNA mischarging in Animalia
oleh: Santosh Kumar Kuncha, Mohd Mazeed, Raghvendra Singh, Bhavita Kattula, Satya Brata Routh, Rajan Sankaranarayanan
| Format: | Article |
|---|---|
| Diterbitkan: | Nature Portfolio 2018-02-01 |
Deskripsi
The number of tRNA isodecoders has expanded significantly during evolution, which has resulted in ambiguity in tRNA selection by synthetases. Here the authors identify and characterize a dedicated proofreading factor that eliminates errors caused by ambiguity in tRNA selection by eukaryotic tRNA synthetases.