Genome-wide deposition of 6-methyladenine in human DNA reduces the viability of HEK293 cells and directly influences gene expression

oleh: Julian Broche, Anja R. Köhler, Fiona Kühnel, Bernd Osteresch, Thyagarajan T. Chandrasekaran, Sabrina Adam, Jens Brockmeyer, Albert Jeltsch

Format: Article
Diterbitkan: Nature Portfolio 2023-02-01

Deskripsi

Global introduction of m6dA into human DNA in HEK293 cells reduces their viability and directly alters their gene expression.