Essential role for a novel population of binucleated mammary epithelial cells in lactation
oleh: Anne C. Rios, Nai Yang Fu, Paul R. Jamieson, Bhupinder Pal, Lachlan Whitehead, Kevin R. Nicholas, Geoffrey J. Lindeman, Jane E. Visvader
| Format: | Article |
|---|---|
| Diterbitkan: | Nature Portfolio 2016-04-01 |
Deskripsi
The main function of the mammary gland is to produce milk to sustain offspring. Here, the authors show that secretory alveolar cells in the lactating gland in several species are binucleated, which increases milk production, and that binucleation is regulated by Aurora kinase-A and Polo-like kinase-1.