Affinity of anti-spike antibodies to three major SARS-CoV-2 variants in recipients of three major vaccines
oleh: Patrick J. Macdonald, Jeffrey M. Schaub, Qiaoqiao Ruan, Carroll L. Williams, John C. Prostko, Sergey Y. Tetin
| Format: | Article |
|---|---|
| Diterbitkan: | Nature Portfolio 2022-08-01 |
Deskripsi
Macdonald, Schaub et al. measure apparent antibody affinities to the ACE-2 receptor binding domain of the SARS-CoV-2 spike protein in recipients of the Pfizer, Moderna and J&J vaccines. All vaccinated individuals develop high-affinity antibodies, however the affinities are weaker to Delta and Omicron variants compared to ancestral virus.