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Interpreting molecular similarity between patients as a determinant of disease comorbidity relationships
oleh: Jon Sánchez-Valle, Héctor Tejero, José María Fernández, David Juan, Beatriz Urda-García, Salvador Capella-Gutiérrez, Fátima Al-Shahrour, Rafael Tabarés-Seisdedos, Anaïs Baudot, Vera Pancaldi, Alfonso Valencia
Format: | Article |
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Diterbitkan: | Nature Portfolio 2020-06-01 |
Deskripsi
Disease comorbidity is attracting increasing attention, but the involvement of molecular factors in forecasting risk of a disease in the presence of other diseases is poorly understood. Here the authors build a disease interaction network based on gene expression profile and discover new comorbidity relationships in patient subgroups.