Nitroimidazoles XIII. Synthesis of Substituted (1-Methyl-5-Nitro-2-Imidazolyl) Isoxazoles

oleh: Abbas Shafiee, Mohammad ALi Ebrahimzadeh

Format: Article
Diterbitkan: Iranian Institute of Research and Development in Chemical Industries (IRDCI)-ACECR 1998-12-01

Deskripsi

The beta0diketone derivatives of nitroimidazole were synthesized from the reaction of magnesium salt of beta-ketoaccids 3 with imidazolide 4. The raction of beta-diketones with hydroxylamine hydrochloride afforded either the isoxazoles or the 5-hydroxyl-2-isoxazolines.