Hierarchical zwitterionic modification of a SERS substrate enables real-time drug monitoring in blood plasma
oleh: Fang Sun, Hsiang-Chieh Hung, Andrew Sinclair, Peng Zhang, Tao Bai, Daniel David Galvan, Priyesh Jain, Bowen Li, Shaoyi Jiang, Qiuming Yu
| Format: | Article |
|---|---|
| Diterbitkan: | Nature Portfolio 2016-11-01 |
Deskripsi
Despite the high sensitivity of SERS analysis, non-specific binding of proteins can impact the effectiveness in biologically important media such as blood. Here the authors report a SERS substrate modified to prevent protein fouling and demonstrate drug detection in undiluted plasma.