The WID-BC-index identifies women with primary poor prognostic breast cancer based on DNA methylation in cervical samples

oleh: James E. Barrett, Chiara Herzog, Allison Jones, Olivia C. Leavy, Iona Evans, Susanne Knapp, Daniel Reisel, Tatiana Nazarenko, Yoo-Na Kim, Dorella Franchi, Andy Ryan, Joanna Franks, Line Bjørge, Michal Zikan, David Cibula, Nadia Harbeck, Nicoletta Colombo, Frank Dudbridge, Louise Jones, Karin Sundström, Joakim Dillner, Angelique Flöter Rådestad, Kristina Gemzell-Danielsson, Nora Pashayan, Martin Widschwendter

Format: Article
Diterbitkan: Nature Portfolio 2022-02-01

Deskripsi

Breast cancer is most commonly diagnosed via a needle biopsy. In this study, the authors show that cervical samples from women with breast cancer have a methylation signature different to that of healthy controls.