Palladium-catalysed formation of vicinal all-carbon quaternary centres via propargylation
oleh: Xin Huang, Shangze Wu, Wangteng Wu, Pengbin Li, Chunling Fu, Shengming Ma
| Format: | Article |
|---|---|
| Diterbitkan: | Nature Portfolio 2016-08-01 |
Deskripsi
Formation of vicinal, quaternary stereocentres is challenging, but such products are commonly encountered in nature. Here, the authors report a palladium catalysed process to form vicinal quaternary carbons via propargylation, including in enantiopure form when optically active starting materials are employed.